Lee Do guys actually wear these comfortably and they actually work as intended?
Yes. The comfort is depending on the device. Some of them can harm your health, others are no problem to wear.
Lee -Can I have any objections based on health concerns, either physical or mental?
Depending on the gender. For males, it's really important to have an erection from time to time. Still, for all genders, it's important to keep the device clean.
Forced chastity of course is a no-go. Still it does happen from time to time.